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Home ❯ Advanced Cosmetic Procedures ❯ PDRN Regenerative Skin Rejuvenation in Chicago, IL

PDRN (Polydeoxyribonucleotide) Treatment

Procedure:
45–60 minutes
Recovery:
Minimal; mild redness or tenderness for 24–48 hours

PDRN (Polydeoxyribonucleotide) is a regenerative treatment that harnesses DNA molecules derived from salmon sperm to repair damaged skin, enhance elasticity, and restore a youthful glow. At Elysium Chicago Aesthetics + Longevity, PDRN is used to stimulate tissue regeneration, boost collagen production, and improve overall skin texture—offering a minimally invasive solution for revitalized, radiant skin.

Patients throughout Chicago, River North, and Downtown Chicago trust PDRN therapy for its clinically proven ability to restore balance, repair skin damage, and improve elasticity through advanced bio-cellular regeneration.

Areas We Treat With PDRN Therapy

  • Face and neck for rejuvenation and fine line reduction
  • Décolletage and chest for tone improvement
  • Hands for elasticity and texture refinement
  • Under-eye area for brightening and smoothing
  • Scalp for regenerative support in hair restoration treatments
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Overview

What is PDRN?

PDRN (Polydeoxyribonucleotide) is a naturally derived compound extracted from purified salmon DNA, chosen for its biocompatibility with human skin. When introduced into the skin through microinjections or combined with regenerative treatments, PDRN activates cell repair, enhances tissue regeneration, and promotes deep hydration and elasticity.

This therapy works at the molecular level to stimulate fibroblast activity, increasing collagen and elastin synthesis. The result is healthier, firmer, and more luminous skin with improved texture and reduced fine lines.

At Elysium Chicago, PDRN is often paired with microneedling, PRP, or laser rejuvenation for synergistic results—helping patients achieve brighter, smoother, and more resilient skin with minimal downtime.

What You Can Expect at Our Facility

PDRN Treatment Benefits

  • Repairs and regenerates damaged skin cells
  • Improves elasticity, tone, and hydration
  • Reduces fine lines, dullness, and uneven texture
  • Minimally invasive with little to no downtime
  • Promotes collagen and elastin production
  • Enhances skin barrier and firmness over time
  • Safe and biocompatible for all skin types
“

When it comes to a 5 star experience be it Botox, Fillers, Cheek Augmentation, Facial Rejuvenation, Chemical Peels, Liposuction, Lazer Hair Removal, Cellulite Reduction, Fat Transfer, Skin Mole Removal or indulging in the excellent skin care product lines you will find no better.

Club G.5-Start Review, River North Chicago
“

Have been coming here for 4 years and absolutely love the girls at the office. Victoria also always does an amazing job on my treatments!

Caitlin H.Long-Time Client, Google Review
“

I loved my services from Rachel Deutsch, she has great experience in the industry and is so knowledgeable about all of the treatments and services. All of the staff are so friendly; you are in great hands here.

Zoe B.Treatment Knowledge, River North Chicago

PDRN Treatments

What You Can Expect

Bespoke
Consultation

During your consultation, your provider will evaluate your skin's condition, tone, and treatment goals to determine whether PDRN is best performed as a standalone therapy or combined with regenerative techniques such as PRFM or microneedling.

Refined
Treatment

The treatment involves injecting or microchanneling PDRN into targeted areas to stimulate cellular regeneration and repair. The process takes about 45–60 minutes and is well tolerated with topical numbing.

Visible
Results

Mild redness or swelling may occur for 1–2 days. Noticeable improvements in tone, texture, and radiance appear gradually over several weeks as cellular turnover and collagen renewal increase.
Non-Invasive Cosmetic Surgery Treatments in Chicago

Eligibility

Who Is a Good Candidate for PDRN Therapy?

PDRN therapy is ideal for men and women looking to rejuvenate their skin at the cellular level without downtime or synthetic chemicals.

Questions? Read Our FAQs

You May Be an Ideal Candidate If You:

  • Have dull, uneven, or aging skin
  • Want to improve elasticity and hydration naturally
  • Are in good overall health and not pregnant
  • Prefer a natural, regenerative approach to skin repair

PDRN Treatments in Chicago

Frequently Asked Questions

How does PDRN work?

PDRN activates cellular regeneration and healing by stimulating fibroblast activity and collagen production, promoting skin renewal from within.

Is PDRN safe?

Yes. PDRN is derived from purified salmon DNA, which is highly compatible with human cells and well-tolerated across all skin types.

How many treatments will I need?

A series of 3–4 treatments spaced 3–4 weeks apart is typically recommended, with maintenance sessions every 6–12 months.

When will I see results?

Skin brightness, firmness, and hydration begin improving within 2–3 weeks, with continued benefits as collagen remodeling occurs.

*All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.

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Elysium Aesthetics + Longevity
520 W Erie St Ste 110
Chicago, IL 60654

T: 312.888.9361

Hours

Mon: 10:00AM – 6:00PM
Tue: 9:00AM – 6:00PM
Wed: 9:00AM – 6:00PM
Thu: 9:00AM – 7:00PM
Fri: 9:00AM – 7:00PM
Sat: 10:00AM – 3:00PM
Sun: Closed

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Elysium Chicago
520 W Erie St
Ste 110
Chicago, IL 60654

T: 312.888.9361